Jean M. Elick, Ph.D.

bee-researchASSISTANT PROFESSOR OF BIOCHEMISTRY

Email: jelick@sf.edu
Phone: 260.399.7700, ext. 8221

CURRENT RESEARCH PROJECTS

  1.  Exploring the levels of Neonicotinoid Pesticides in Freshwater Watershed systems and their effects on aquatic macroinvertebrates in North Eastern Indiana.–  chemical-structureIn this project, we are sampling local watershed systems and monitoring neonicotinoid levels.  Neonicotinoids are very similar to nicotine and are a new class of pesticides.  They are in wide use today in agricultural and urban landscapes.  While they are not particularly dangerous to humans, we suspect that they are causing grave damage to the beneficial student-work-jmemacroinvertebrate populations (bugs).  It would be interesting to see if there is a connections between high pesticide levels and low insect populations.  I need help to collect water samples in Fort Wayne and surrounding counties.  I also need help to analyze the water samples for common neonicotinoid pesticides such as clothinanidin or imidacloprid.
  2. Bumblebee Husbandary Project- I am currently working on a smajme-beell project that would develop techniques to manage Bumblebee colonies. Eventually, my team will be able to capture queens in the spring and start 100 or more Bumble colonies.  These will be offered to local farms and nature preserves.  I need help capturing the queens and learning how to keep and maintain the bumble colony.
  3. Bee Group Project– I’m in the process of starting this new group of volunteers at the University of Saint Francis; we hope to connect with other groups that are promoting pollinators.  We will identify ways in which we might organize a “Bumblebjme-bee-2ee Round up” for the purposes of recording species types and populations. We might also develop an outreach to local agricultural groups to promote best practices for pollinators.

PROFESSIONAL EDUCATION  elick-teaching

PH.D. Molecular Biology (1994), Department of Biology, Bowling Green State University, Bowling Green, OH 43403. Thesis Title: “Chemical Probing of Three Way Junction DNA”.

Master of Science, Biochemistry (1992), Department of Chemistry, Bowling Green State University, Bowling Green, OH 43403. Thesis Title:” Chemical Probing of 5S Ribosomal RNA”.

Bachelor of Science with Honors, Dual Major Chemistry and Biology with Emphasis in Toxicology (1985).  Department of Biology, Department of chemistry, Tri-State University, Angola, IN 46703.

EXPERTISE

  • Biochemistry
  • Molecular Biology

SPECIALIZED TRAINING

  • Prokaryote, Eukaryote, and Mammalian Cell Culturing, Cloning
  • Chemical Probing of Nucleic Acid Structure, RNase Protection Assays, Nuclease Footprinting
  • Gel Shift Analysis, Western Blot Analysis, working with RNA and Radioisotopes
  • Phosphorimage Analysis, Molecular Modeling, Northern Blot Analysis
  • Immunoprecipitation, Glutathinone Fusion Proteins, and Retic Lysate Translation Assays

PUBLICATIONS

  • Nussbaum, J.M., M. Major, S. Gunnery. (2003). “Transcriptional Upregulation of Interferon-Induced Protein Kinase, PKR, In Breast Cancer”.   Cancer Letters, 196, 207-216.
  • Nussbaum, J. M., S. Gunnery, M. B. Mathews, (2002)  “The 3’Untranslated regions of cytoskeletal muscle mRNAs inhibit translation by activating the doublestranded RNA-dependent protein kinase PKR”. Nucleic Acids Research 30(5), 1205-1212.
  • Celander, D. W., J. M. Nussbaum (1996). “Efficient Modification of RNA by Porphyrin Cation Photochemistry: Monitoring the Folding of Coaxially Stacked RNA Helices in tRNAPhe and the Human Immunodeficiency Virus Type 1 Rev Response Element RNA”. Biochemistry 35(37), 12061-12069.
  • Leontis, N. B., M. Piotto, M. T. Hills, A. Malhotra, I. V. Ouporov, J. M. Nussbaum, and D. G. Gorenstein (1995). “Structural Studies of DNA Three-Way Junctions.” Methods in Enzymology. 261, 183-207.
  • Nussbaum, J.M., M. E. Newport, M. Mackie, and N. B. Leontis (1994). “Structure-Specific Binding and Photo-Sensitized Cleavage of Branched DNA Three-Way Junction Complexes by Cationic Porphyrins.” Photochemistry and Photobiology 59, 515-528.
  • Leontis, N. B., M. T. Hills, M. Piotto, A. Malhotra, J. Nussbaum and D. G. Gorenstein (1993). “A Model of the Solution Structure of a Branched Three-Strand DNA Complex.” Journal of Biomolecular Structure Dynamics. 11, 215-223.

PROFESSIONAL EXPERIENCE

Associate Professor– Since August 2000- present

Supervisor: Dr. Andrea Geyer, Associate Professor, Department of Chemistry, University of Saint Francis, Fort Wayne, IN 46808

Courses taught:

  • Introductory Chemistry (CHEM 121)
  • Principles of Chemistry (CHEM 141-142)
  • Principles of Chemistry Laboratory (CHEM 141-142)
  • General Organic Biochemistry for pre-nursing students (CHEM 243)
  • General Organic Biochemistry Laboratory for pre-nursing students (CHEM 243)
  • Biochemistry (CHEM 333)
  • Biotechnology Laboratory (CHEM 367)

Chair of the Department of Chemistry– January 2009 to August 2015

Department of Chemistry, University of Saint Francis, Fort Wayne, IN 46808

  • Supervised 4 faculty and 2-5 adjuncts each year
  • Director of 4 Bachelor’s Degree and 1 Associate Degree programs

Adjunct Professor- Summer of 2000

Supervisor: Professor Ildy Boer, Associate Professor, Department of Chemistry and Biochemistry, Community College, of Morris. Randolph, NJ

Courses taught:

  • Introductory Chemistry for pre- nursing students

Lab Manager/Research Assoicate- 1996 to 2000

Supervisor: Dr.Shobha Gunner, Instructor, Department of Biochemistry and Molecular Biology, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103

Responsibilities:

  • Managing and organizing a laboratory of twelve scientist
  • Maintaining several mammalian cell lines and critical lab stocks
  • Responsible for the organization of valuable technical information
  • Scientific interests include the study of cellular RNAs and their ability to activate the transnational regulatory protein, PKR

Postdoctoral Fellowship- 1994 to 1996

Advisor: Dr. Daniel W. Celander, Associate Professor, Department of Microbiology, University of Illinois

Responsibilities:

  • Further characterized a small set of Cationic Porphyrin probes which I developed during my doctorate, as indicators of RNA structure.
  • The novel compounds were used to probe the Tetrahymena Group I Intron and the Rev Responsive Element.

Research Assistant – 1987 to 1994

Department of Chemistry Bowling Green State University

Responsibilities:

  • Assisted in proctoring and grading examinations in General Chemistry and Inorganic Chemistry
  • Assisted in teaching General Chemistry Laboratories
  • Assisted in teaching Biochemistry Laboratories
  • Tutored Organic Chemistry

Research Technician- 1987

Advisor: Dr. A.F. Pearlmutter, Associate Profressor, Department of Biochemistry, The Medical College of Ohio, Toledo

Research Technician- 1985 to 1987

Advisor: Dr. James H. Freisheim, Department Chairman, Department of Biochemistry,  The Medical College of Ohio, Toledo